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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Introduction of Epiphen Tablet

Epiphen Tablet is a combination of two medicines used in the treatment and prevention of epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Epiphen Tablet is a combination of barbiturate and sodium channel modulators (AED).

Uses of Epiphen Tablet

Benefits of Epiphen Tablet

In Epilepsy

Epiphen Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.

Side effects of Epiphen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epiphen

  • Nausea
  • Vomiting
  • Vertigo
  • Nystagmus (involuntary eye movement)
  • Double vision
  • Sleepiness
  • Anemia (low number of red blood cells)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Gingival hypertrophy (gum enlargement)
  • Softening of bones
  • Abnormal hair growth

How to use Epiphen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epiphen Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Epiphen Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Epiphen Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Epiphen Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Baby should be monitored for excessive sleepiness and weight gain.
Driving
UNSAFE
Epiphen Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Epiphen Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epiphen Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Epiphen Tablet should be used with caution in patients with liver disease. Dose adjustment of Epiphen Tablet may be needed. Please consult your doctor.

What if you forget to take Epiphen Tablet?

If you miss a dose of Epiphen Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Epiphen Tablet
₹2.0/Tablet
₹4.12/tablet
106% costlier
Phenytal 50 mg/100 mg Tablet
Intas Pharmaceuticals Ltd
₹1.78/tablet
11% cheaper
Epiphen 50 mg/100 mg Tablet
Reliance Formulation Pvt Ltd
₹2.5/tablet
25% costlier
₹2/tablet
same price
Episol Plus 50 mg/100 mg Tablet
Psychotropics India Ltd
₹1.25/tablet
38% cheaper

Quick tips

Epiphen Tablet

  • You have been prescribed Epiphen Tablet to treat and prevent epilepsy (seizures).
  • Always make sure that that you have a sufficient amount of medicine present with you.
  • It may increase blood sugar levels. Monitor your sugar level regularly and inform your doctor if you see a spike in your levels.
  • Epiphen Tablet may cause swollen gum (gum hypertrophy), hence take care of oral or dental hygiene.
  • Lifestyle changes like regular light exercise and a stress free life along with a healthy diet can help the medicine work better.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

Patient concerns

arrow
3-4 attack of strokes in 3 yrs nothing found in CT scan & EEG.these tests are done again after 3 months. But nothing found. Doctors prescribed me Oxetol 450 mg.doctor say course of medicine is 2-3 yrs.I drink and smoke addicted to drug I don't understand if the test show nothing then why strokes happens to me?
Dr. Vikas Sharma
Neurology
is it stroke or epilepsy; as u are on medicine for epilepsy
Sir i use in tablets phenytion Last two months i use this tablets
Dr. Jyoti Kapoor Madan
Psychiatry
It's treatment for epilepsy.
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References

  1. MedIndia. Phenobarbital. [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. Phenobarbital. Montréal, Canada: PENDOPHARM; 2018. [Accessed 22 Apr. 2019] (online) Available from:External Link

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