Endoxan Asta 500mg Injection
Prescription Required
Product introduction
Endoxan Asta 500mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
Endoxan Asta 500mg Injection is used in the treatment of many types of cancer
Endoxan Asta 500mg Injection is used in the treatment of many types of cancer
Uses of Endoxan Injection
Benefits of Endoxan Injection
In Cancer
Endoxan Asta 500mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Endoxan Asta 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Nephrotic syndrome
Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine accompanied with excessive swelling over various parts of the body such as around the eyes and in the feet and ankles. Endoxan Asta 500mg Injection works by suppressing the immune system thereby reducing inflammation and swelling that occur in nephrotic syndrome. It reduces the protein in the urine and also helps in getting rid of the extra fluid, thereby relieving the swelling over different parts of the body. This helps to restore the normal kidney function and prevents further damage to the kidneys.
Side effects of Endoxan Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endoxan
- Vomiting
- Nausea
- Hair loss
- Fever
- Blood in urine
- Diarrhea
- Decreased white blood cell count (neutrophils)
How to use Endoxan Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Endoxan Injection works
Endoxan Asta 500mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Endoxan Asta 500mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Endoxan Asta 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Endoxan Asta 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Endoxan Asta 500mg Injection may cause side effects which could affect your ability to drive.
Endoxan Asta 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Endoxan Asta 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney
CAUTION
Endoxan Asta 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan Asta 500mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Endoxan Asta 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Endoxan Asta 500mg Injection may be needed. Please consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Endoxan Asta 500mg Injection helps in the treatment of cancer.
- It is injected into the vein by a doctor or healthcare professional.
- Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
- Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
- You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
- Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
- Do not take Endoxan Asta 500mg Injection if you are pregnant or breastfeeding.
- Use effective contraception method to prevent pregnancy while taking this medicine.
Fact Box
Chemical Class
Nitrogen Mustard Compounds
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent
Patient concerns
FAQs
Can Endoxan Asta 500mg Injection cause infertility?
Yes, Endoxan Asta 500mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Endoxan Asta 500mg Injection.
Do I need to avoid sun exposure during treatment with Endoxan Asta 500mg Injection?
No, there is no evidence that you need to avoid sun exposure while on Endoxan Asta 500mg Injection. Skin and nail discoloration are reported rarely with Endoxan Asta 500mg Injection.
Can Endoxan Asta 500mg Injection cause cancer?
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Endoxan Asta 500mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Endoxan Asta 500mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Is Endoxan Asta 500mg Injection chemotherapy medicine?
Yes, Endoxan Asta 500mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Can Endoxan Asta 500mg Injection be used for non-cancer condition?
Yes, Endoxan Asta 500mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Endoxan Asta 500mg Injection for nephrotic syndrome has not been established.
Can Endoxan Asta 500mg Injection causes weight loss?
Yes, Endoxan Asta 500mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
- Cyclophosphamide monohydrate. Camberley, Surrey: Sandoz Limited; 2014 [revised 07 Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
- Cyclophosphamide. Baxter Health Corporation; 1959. [Accessed 26 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
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