Duopil 1/500 Tablet PR
Prescription Required
Product introduction
Duopil 1/500 Tablet PR belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.
Duopil 1/500 Tablet PR is used in the treatment of type 2 diabetes mellitus . It is a combination medicine that can control blood sugar better than single medication. It should be used along with a proper diet and regular exercise for best results. Hypoglycemia (low blood sugar level) may occur as a side effect and it should be taken with food to avoid upset stomach.
Duopil 1/500 Tablet PR is used in the treatment of type 2 diabetes mellitus . It is a combination medicine that can control blood sugar better than single medication. It should be used along with a proper diet and regular exercise for best results. Hypoglycemia (low blood sugar level) may occur as a side effect and it should be taken with food to avoid upset stomach.
Uses of Duopil Tablet PR
Benefits of Duopil Tablet PR
In Treatment of Type 2 diabetes mellitus
Duopil 1/500 Tablet PR is a combination medicine that increases the amount of insulin your body produces (in the pancreas). The insulin then works to lower your blood glucose level. It is usually taken once a day. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Side effects of Duopil Tablet PR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duopil
- Hypoglycemia (low blood glucose level)
- Headache
- Nausea
- Diarrhea
- Flatulence
How to use Duopil Tablet PR
Use it as advised by your doctor or check the label for directions before use. Duopil 1/500 Tablet PR is to be taken with food.
How Duopil Tablet PR works
Duopil 1/500 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin.Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Duopil 1/500 Tablet PR.
Pregnancy
CONSULT YOUR DOCTOR
Duopil 1/500 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
UNSAFE
Duopil 1/500 Tablet PR is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Duopil 1/500 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Duopil 1/500 Tablet PR may be needed. Please consult your doctor.
Use of Duopil 1/500 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Use of Duopil 1/500 Tablet PR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Duopil 1/500 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Duopil 1/500 Tablet PR may be needed. Please consult your doctor.
Duopil 1/500 Tablet PR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
Duopil 1/500 Tablet PR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
What if you forget to take Duopil Tablet PR?
If you miss a dose of Duopil 1/500 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Quick tips
- You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
- You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Duopil 1/500 Tablet PR.
- Take it with food to lower your chance of having an upset stomach.
- Monitor your blood sugar level regularly while you are taking this medicine.
- It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Duopil 1/500 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
- Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
User feedback
Patients taking Duopil 1/500 Tablet PR
Once A Day
75%
Twice A Day
25%
What are you using Duopil Tablet PR for?
Type 2 diabet*
100%
*Type 2 diabetes
How much was the improvement?
Excellent
67%
Average
33%
What were the side-effects while using Duopil 1/500 Tablet PR?
No Side Effec*
100%
*No Side Effect
How do you take Duopil Tablet PR?
Empty stomach
100%
Please rate Duopil 1/500 Tablet PR on price
Expensive
67%
Average
33%
FAQs
What are the recommended storage conditions for Duopil 1/500 Tablet PR?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can the use of Duopil 1/500 Tablet PR lead to lactic acidosis?
Yes, the use of Duopil 1/500 Tablet PR can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin-associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is considered to be harmful for patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Duopil 1/500 Tablet PR and consult your doctor immediately.
What is Duopil 1/500 Tablet PR?
Duopil 1/500 Tablet PR is a combination of two medicines: Glimepiride and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.
What are the possible side effects of Duopil 1/500 Tablet PR?
The use of Duopil 1/500 Tablet PR is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
Can the use of Duopil 1/500 Tablet PR lead to Vitamin B12 deficiency?
Yes, the use of Duopil 1/500 Tablet PR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can experience tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.
Can the use of Duopil 1/500 Tablet PR cause hypoglycemia?
Yes, the use of Duopil 1/500 Tablet PR can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.
Is it safe to take alcohol while I am also taking Duopil 1/500 Tablet PR?
No, it is not safe to take Duopil 1/500 Tablet PR along with alcohol, as it may lower your blood sugar levels and lead to hypoglycemia. It can also increase the chances of lactic acidosis.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:
- Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
- American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 28 Oct. 2021] (online) Available from:
Marketer details
Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Country of origin: India
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