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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Introduction of Domsi Plus Tablet

Domsi Plus 10mg/5mg/325mg Tablet is a prescription medicine used in the treatment of migraine. It prevents pain signals and fever associated with migraine. It also blocks certain substances in the brain that trigger nausea or vomiting during migraine headaches.

Domsi Plus 10mg/5mg/325mg Tablet is a combination of dopamine (D2) receptor antagonist-prokinetic agent, calcium channel blocker-migraine prevention, and analgesic and antipyretic-PCM.

Uses of Domsi Plus Tablet

Benefits of Domsi Plus Tablet

In Migraine

Domsi Plus 10mg/5mg/325mg Tablet is a combination of medicines that treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Domsi Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Domsi Plus

  • Weight gain
  • Drowsiness
  • Dryness in mouth

How to use Domsi Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Domsi Plus 10mg/5mg/325mg Tablet is to be taken empty stomach.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Domsi Plus 10mg/5mg/325mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Domsi Plus 10mg/5mg/325mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Domsi Plus 10mg/5mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Domsi Plus 10mg/5mg/325mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Domsi Plus 10mg/5mg/325mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Domsi Plus 10mg/5mg/325mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Domsi Plus 10mg/5mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Domsi Plus 10mg/5mg/325mg Tablet may be needed. Please consult your doctor.
However, the use of Domsi Plus 10mg/5mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Domsi Plus Tablet?

If you miss a dose of Domsi Plus 10mg/5mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Domsi Plus 10mg/5mg/325mg Tablet
₹5.74/Tablet
Zerograin-Plus Tablet
Mankind Pharma Ltd
₹5.86/tablet
2% costlier
Migrasaf Tablet
SAF Fermion Ltd
₹10.1/tablet
76% costlier
₹4/tablet
30% cheaper
Conizine P 10mg/5mg/325mg Tablet
Novalab Healthcare Pvt Ltd
₹4.8/tablet
16% cheaper
₹6.5/tablet
13% costlier

Quick tips

Domsi Plus Tablet

  • Domsi Plus 10mg/5mg/325mg Tablet helps to ease the pain you feel during a migraine headache as well as helps to stop you from feeling sick.
  • It can make you feel dizzy, rise slowly if you have been sitting or lying down for a long time.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Domsi Plus 10mg/5mg/325mg Tablet can only decrease the number and severity of attacks but may not completely stop them.
  • Some tips that may help avoid a migraine attack:
    1. Have your meals at the same time every day.
    2. Avoid bright lights and extreme temperatures.
    3. Avoid loud music and noisy places.
    4. Avoid chocolates,  cheese, processed food, alcohol, and smoking.
    5. f) Get sufficient sleep and avoid stress.

Fact Box

Habit Forming
No
Therapeutic Class
NEURO CNS

Patient concerns

Patient concerns

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I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me
Dr. Pushkar Mani
Physician
it could be migraine
arrow

FAQs

Domsi Plus Tablet

Q. Can I stop taking Domsi Plus 10mg/5mg/325mg Tablet when my migraine symptoms are relieved?

Domsi Plus 10mg/5mg/325mg Tablet is used in the treatment of migraine attack. This medicine should be continued as advised by the doctor.

Q. Can I drink alcohol while using Domsi Plus 10mg/5mg/325mg Tablet?

No, you should not drink alcohol using Domsi Plus 10mg/5mg/325mg Tablet. Drinking alcohol while taking Domsi Plus 10mg/5mg/325mg Tablet can make you feel very drowsy and sleepy.

Q. Can the use of Domsi Plus 10mg/5mg/325mg Tablet cause dry mouth?

Yes, the use of Domsi Plus 10mg/5mg/325mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.

Q. What can cause or trigger a migraine attack?

Certain physical or environmental factors, such as foods, hormonal changes, weather, and stress, can lead to or “trigger” a migraine. However, it’s important to remember that triggers are different for everyone. That’s why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones don’t. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.

Q. Can I take a higher dose of this medicine than recommended?

No, taking higher than recommended dose of Domsi Plus 10mg/5mg/325mg Tablet can lead to increased side effects. If you are experiencing increased severity of migraine attacks, which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the instructions for the storage and disposal of Domsi Plus 10mg/5mg/325mg Tablet?

Keep this medicine in the packet or container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Q. Can the Domsi Plus 10mg/5mg/325mg Tablet cause sleepiness?

Domsi Plus 10mg/5mg/325mg Tablet can cause sleepiness, dizziness or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2017. [Accessed 15 Feb. 2019] (online) Available from:External Link
  2. Sibelium. Ringaskiddy, Ireland: Janssen Sciences Ireland UC; 2019. [Accessed 15 Feb. 2019] (online) Available from:External Link
  3. ScienceDirect. Flunarizine. [Accessed 12 Apr. 2019] (online) Available from:External Link

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