Denoclast Injection
Prescription Required
Product introduction
Denoclast Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures.
is used in the treatment osteoarthritis
Uses of Denoclast Injection
Benefits of Denoclast Injection
In Osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Denoclast Injection slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered.
You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
Side effects of Denoclast Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Denoclast
- Musculoskeletal (bone, muscle or joint) pain
- Pain in extremities
- Nerve pain
- Constipation
- Rash
- Urinary tract infection
How to use Denoclast Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Denoclast Injection. Please consult your doctor.
Pregnancy
UNSAFE
Denoclast Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Denoclast Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Denoclast Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Denoclast Injection is safe to use in patients with kidney disease. No dose adjustment of Denoclast Injection is recommended.
Liver
SAFE IF PRESCRIBED
Denoclast Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Denoclast Injection may not be needed in these patients. Please consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
Denoclast Injection
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Quick tips
- Denoclast Injection is a medication used to treat thinning of the bones (called osteoporosis).
- Take calcium and vitamin D to help build your bones when taking Denoclast Injection.
- Do not take if you are pregnant or plan to become pregnant.
- May cause a rare problem of the jaw (osteonecrosis), mostly seen after a dental procedure. Tell your doctor if you develop sudden jaw pain.
- Denoclast Injection may also increase the risk of infection. Avoid being close to people with cold, flu or other contagious illnesses.
- Tell your doctor if you develop a rash while taking Denoclast Injection.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Bone resorption inhibitors- Monoclonal antibodies
Patient concerns
FAQs
How long can you stay on Denoclast Injection?
There is no optimal duration of treatment of osteoporosis with Denoclast Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Denoclast Injection. Depending on this, the duration of taking Denoclast Injection is decided.
Does Denoclast Injection cause hair loss?
Yes, hair loss is a common side effect of Denoclast Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
Is Denoclast Injection a chemotherapy drug?
Denoclast Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Denoclast Injection makes the bones stronger and less likely to break.
How is Denoclast Injection given and how often?
Denoclast Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Denoclast Injection.
Can Denoclast Injection be taken during pregnancy?
No, pregnant women should not take Denoclast Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Denoclast Injection if you can become pregnant.
How should Denoclast Injection be stored?
Denoclast Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
Does Denoclast Injection cause osteonecrosis of the jaw?
Osteonecrosis is a rare side effect of Denoclast Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Denoclast Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
- Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1299.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 370.
- Drugs.com. Denosumab. [Accessed 02 Apr. 2019] (online) Available from:
- Denosumab. Milton Road, Cambridge: Amgen Ltd.; 2010 [revised Jun. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
Marketer details
Name: Zydus Healthcare Limited
Address: Zydus Tower, CTS No- 460/6 of Village Pahadi, Off I. B. Patel Road, Goregaon (East), Mumbai-400 063
Country of origin: India
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₹21000
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1.0 ml in 1 prefilled syringe
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