Darzalex 400mg Injection
Prescription Required
Product introduction
Darzalex 400mg Injection is used in the treatment of multiple myeloma, which is a type of cancer of plasma cells.
Darzalex 400mg Injection is given as an IV infusion into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Infusion reaction such as swollen face, lips, mouth, tongue or throat, difficulty swallowing or breathing are very common side effects. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells while taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Darzalex 400mg Injection is given as an IV infusion into veins under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Infusion reaction such as swollen face, lips, mouth, tongue or throat, difficulty swallowing or breathing are very common side effects. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells while taking this medicine.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Uses of Darzalex Injection
Benefits of Darzalex Injection
In Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Darzalex 400mg Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
Side effects of Darzalex Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Darzalex
- Back pain
- Constipation
- Decreased white blood cell count (neutrophils)
- Diarrhea
- Dizziness
- Fatigue
- Fever
- Infusion reaction
- Insomnia (difficulty in sleeping)
- Joint pain
- Low blood platelets
- Nausea
- Breathlessness
- Upper respiratory tract infection
- Vomiting
How to use Darzalex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Darzalex 400mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Darzalex 400mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Darzalex 400mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Darzalex 400mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Darzalex 400mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Darzalex 400mg Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Darzalex 400mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Darzalex 400mg Injection may not be needed in these patients. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Darzalex 400mg Injection is given in combination with other medicines for the treatment of multiple myeloma.
- Drink at least two to three quarts of fluid every 24 hours while on treatment with Darzalex 400mg Injection, unless you are instructed otherwise.
- To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
- Avoid sun exposure. Wear SPF 30 (or higher) sunblock and protective clothing.
- Do not receive any kind of immunization or vaccination without your doctor's approval while taking Darzalex 400mg Injection.
- Use contraceptives, and avoid getting pregnant while taking Darzalex 400mg Injection. Barrier methods of contraception, such as condoms, should be used during treatment and for 3 months after the last dose of Darzalex 400mg Injection.
- Before receiving Darzalex 400mg Injection inform your doctor if you have a history of breathing problems or hepatitis B infection.
- Let your doctor know if you are pregnant or plan to become pregnant or breastfeeding.
Fact Box
Chemical Class
Carboxylic acid derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Janssen Biotech, Inc. Darzalex (Daratumumab). [Accessed 29 Oct. 2019] (online) Available from:
- Daratumumab [FDA Label]. Horsham, PA: Janssen Biotech, Inc.; 2015 [revised Jun. 2019]. [Accessed 29 Oct. 2019] (online) Available from:
Marketer details
Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Country of origin: United states
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1.0 Injection in 1 vial
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