Combutol 400 Tablet
Prescription Required
Product introduction
Combutol 400 Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
It is an antibiotic.
It is an antibiotic.
Uses of Combutol Tablet
Benefits of Combutol Tablet
In Tuberculosis (TB)
Combutol 400 Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Combutol Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combutol
- Visual impairment
- Color blindness
How to use Combutol Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combutol 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Combutol 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Combutol 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Combutol 400 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Combutol 400 Tablet may cause side effects which could affect your ability to drive.
Combutol 400 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Combutol 400 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combutol 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combutol 400 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combutol 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Combutol 400 Tablet may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Combutol 400 Tablet
₹2.48/Tablet
Mycobutol 400 Tablet
Cadila Pharmaceuticals Ltd
₹2.52/tablet
2% costlier
Themibutol 400mg Tablet
Themis Medicare Ltd
₹2.29/tablet
8% cheaper
Ebutol 400mg Tablet
Novartis India Ltd
₹2.05/tablet
17% cheaper
Koxylar 400mg Tablet
Lark Laboratories Ltd
₹1.53/tablet
38% cheaper
ALBUTOL 400MG TABLET
Alkem Laboratories Ltd
₹0.72/tablet
71% cheaper
Quick tips
- Combutol 400 Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
- It has to be taken for several months in order for it work properly (usually 6 months).
- Take it with food to avoid stomach upset.
- It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
- Avoid consuming alcohol while taking this medication.
- Do not stop taking Combutol 400 Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.
Fact Box
Chemical Class
1,2-Aminoalcohols
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycobacterial cell wall inhibitors-Ethambutol
Patient concerns
User feedback
Patients taking Combutol 400 Tablet
Once A Day
92%
Twice A Day
7%
Alternate Day
1%
What are you using Combutol Tablet for?
Tuberculosis *
100%
*Tuberculosis (TB)
How much was the improvement?
Excellent
100%
FAQs
My child vomited after taking Combutol 400 Tablet. What should be done?
If your child vomited within 30 minutes of taking Combutol 400 Tablet, give the same dose again. If vomiting occurred 30 minutes after taking Combutol 400 Tablet, you need not repeat the dose. If your child vomits again after taking Combutol 400 Tablet, consult your doctor.
For how long does Combutol 400 Tablet stay in your system?
Combutol 400 Tablet stays for about 24 hours in your system. This duration varies from person to person and maybe different for patients with kidney problems.
Will Combutol 400 Tablet work if I have developed tuberculosis for the second time?
Yes, it will work if you had taken proper treatment and got cured when you developed tuberculosis for the first time. If you have any doubt, ask your doctor.
Is it necessary to take so many TB drugs simultaneously? Is there no single medicine which can provide a cure for tuberculosis?
Yes, it is important that you take all the prescribed TB drugs together for the recommended duration, else you will not be cured. A single drug is not prescribed to treat TB because it may increase the risk of developing multi-drug resistant tuberculosis, which is very difficult to treat.
What is drug resistance? Can I become resistant to Combutol 400 Tablet?
Sometimes it happens that bacteria gets modified in your body and stops reacting to the medicine. As a result, the medicine stops working. This is called drug resistance. Drug resistance is uncommon if Combutol 400 Tablet is used in combination with other TB drugs.
Can Combutol 400 Tablet treatment be taken for more than two months?
Yes, Combutol 400 Tablet can be continued for more than 2 months, depending on your condition and as per your doctor’s advice. If after 2 months, your investigations show that the TB bacteria are still active, you may have to take Combutol 400 Tablet for 1 more month. In case you are resistant to other TB drugs, you may have to take Combutol 400 Tablet and other TB drugs (for which you are not drug resistant) for longer than 2 months.
What are the warning signals which should prompt me to stop taking Combutol 400 Tablet?
You should consult your doctor and consider stopping the medicine immediately if you develop any vision problems like blurred vision, color blindness or any kidney problems like decreased amount of urine and swelling of your legs and feet. You may even develop liver troubles like nausea, vomiting and yellowish color of skin and eyes. Beware of all these symptoms and consult your doctor immediately.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1558-559.
- Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 826-27.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 506.
- Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 01 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
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