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PhD (Pharmacology), PGDPRA
Reviewed By
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Introduction of C Koff Syrup

C Koff Syrup is a combination medicine used in the treatment of dry cough. It relieves allergy symptoms such as runny nose, stuffy nose, throat irritation, sneezing, watery eyes and congestion or stuffiness.

C Koff Syrup is a combination of first generation H1 antihistaminic and opioid medicines.

Uses of C Koff Syrup

Benefits of C Koff Syrup

In Dry cough

A dry cough is a cough where no phlegm or mucus is produced. It may cause a tickling sensation or itching in the throat and may be due to cold, flu, allergies or throat irritants. C Koff Syrup suppresses severe dry cough and gives you relief from an itchy throat. Apart from this, it also reduces symptoms of allergy like watery eyes, sneezing and runny nose. Along with taking C Koff Syrup, gargling with warm salt water and having ginger or honey can help you manage dry cough.

Side effects of C Koff Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of C Koff

  • Nausea
  • Vomiting
  • Constipation
  • Sleepiness
  • Lightheadedness
  • Dizziness
  • Breathlessness
  • Sweating

How to use C Koff Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. C Koff Syrup may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
UNSAFE
C Koff Syrup may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
C Koff Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
C Koff Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Larger doses or prolonged use of C Koff Syrup may cause sleepiness and other effects in the baby
Driving
UNSAFE
C Koff Syrup may cause side effects which could affect your ability to drive.
As C Koff Syrup may cause dizziness, blurred vision or the inability to think clearly.
Kidney
SAFE IF PRESCRIBED
C Koff Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of C Koff Syrup may not be needed in these patients. Please consult your doctor.
Use of C Koff Syrup may cause excessive sleepiness in patients with end stage kidney disease.
Liver
CAUTION
C Koff Syrup should be used with caution in patients with liver disease. Dose adjustment of C Koff Syrup may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
C Koff Syrup
₹57.13/Syrup
₹26.21/syrup
54% cheaper
Exiplon Syrup
Khandelwal Laboratories Pvt Ltd
₹36/syrup
37% cheaper
Sothrex C Syrup
Psychotropics India Ltd
₹31.62/syrup
45% cheaper
Codril Syrup
Radicura Pharma pvt ltd
₹68.58/syrup
20% costlier
Phensicod Cough Syrup
Mercury Laboratories Ltd
₹96/syrup
68% costlier

Quick tips

C Koff Syrup

  • C Koff Syrup is prescribed to get relief from a dry cough.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
  • Inform your doctor if you have a history of stomach ulcers or asthma.
  • Consult your doctor if you do not see any improvement and have cough for more than 7 days.

Fact Box

Habit Forming
Yes
Therapeutic Class
RESPIRATORY

Patient concerns

Patient concerns

arrow
medicine required for cough & c
Dr. Pushkar Mani
Physician
Syrup Grilinctus BM 5ml three times for 5 days
Hello doctor, I am suffering from severe c Severe cold and cough since one week frequent spitting is there dry cough feeling hard when coughing advise the natural remedy or best syrup. Thanks
Dr. Shubhra Chandhan Pradhan
ENT
It can be rhinosinusitis, pharyngitis, chest infection. Consult a ENT specialist. Needs proper clinical examination
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User feedback


FAQs

C Koff Syrup

Can the use of C Koff Syrup cause sleepiness or drowsiness?

Yes, C Koff Syrup may make you feel drowsy or sleepy. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

What are the instructions for storage and disposal of C Koff Syrup?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Are there any serious side effects associated with the use of C Koff Syrup?

Serious side effects with C Koff Syrup are uncommon and rare. Tell your doctor as soon as possible if you notice allergic reactions, skin rash or peeling, mouth ulcers, breathing problems, unexplained bleeding, recurrent fevers or infections, vision disturbances, fast or irregular heartbeat.

Will C Koff Syrup be more effective if taken in more than recommended dose?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms while taking this medicine, please consult your doctor.

Can I breastfeed while taking C Koff Syrup?

No, it is not advisable to breastfeed while using C Koff Syrup. This medicine contains Chlorpheniramine, an antihistamine, which can pass into the breast milk and may harm the baby. Inform your doctor if you are breastfeeding a baby.

Can the use of C Koff Syrup cause constipation?

Yes, the use of C Koff Syrup can cause constipation. To prevent constipation, eat high-fiber foods like vegetables, fruits and cereals. Drink plenty of water. Exercise regularly by engaging in activities like swimming, jogging or taking a short walk. Talk to your doctor if constipation persists for a long time.

Can I drink alcohol while taking C Koff Syrup?

No, avoid drinking alcohol while taking C Koff Syrup. Drinking alcohol will increase the risk of serious side effects caused by C Koff Syrup.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Medscape. Chlorpheniramine + Codeine. [Accessed 18 Apr. 2019] (online) Available from:External Link
  2. Chlorpheniramine + Codeine. Colorado Springs: Provident Pharmaceuticals. [Accessed 18 Apr. 2019] (online) Available from:External Link
  3. Codeine phosphate and Chlorpheniramine maleate. Irvine, California: Nexgen Pharma, Inc.; 1985 [revised Jan. 2016]. [Accessed 18 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Surya Pharmaceutical Ltd
Address: Off. 71, Krishna Bagh, Nagwa, Distt.-Varanasi – 221 005 (U.P.) INDIA
Country of origin: India

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