Bozetan 125mg Tablet
Prescription Required
Product introduction
Bozetan 125mg Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.
Bozetan 125mg Tablet is an endothelin receptor antagonist.
Bozetan 125mg Tablet is an endothelin receptor antagonist.
Uses of Bozetan Tablet
Benefits of Bozetan Tablet
In Pulmonary arterial hypertension (PAH)
Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Bozetan 125mg Tablet relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.
Side effects of Bozetan Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bozetan
- Headache
- Ankle swelling
- Edema (swelling)
- Diarrhea
- Anemia (low number of red blood cells)
- Respiratory tract infection
How to use Bozetan Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bozetan 125mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety advice
Alcohol
UNSAFE
Bozetan 125mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
UNSAFE
Bozetan 125mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Bozetan 125mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Bozetan 125mg Tablet may cause side effects which could affect your ability to drive.
As Bozetan 125mg Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive.
As Bozetan 125mg Tablet can induce hypotension (decrease of your blood pressure) which can make you feel dizzy and this can affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Bozetan 125mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Bozetan 125mg Tablet is recommended.
Liver
CAUTION
Bozetan 125mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bozetan 125mg Tablet may be needed. Please consult your doctor.
Use of Bozetan 125mg Tablet is not recommended in patients with moderate and severe liver disease.
Use of Bozetan 125mg Tablet is not recommended in patients with moderate and severe liver disease.
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Quick tips
- Your doctor has prescribed Bozetan 125mg Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
- It helps improve your quality of life, exercising ability, and delay disease progression.
- Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
- Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
- Do not drive or do anything requiring concentration until you know how Bozetan 125mg Tablet affects you.
- Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Bozetan 125mg Tablet as it is toxic to an unborn baby.
- Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
- Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Fact Box
Chemical Class
Sulfonamide and Pyrimidine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Endothelin receptor blocker
Patient concerns
FAQs
How is Bozetan 125mg Tablet administered?
Bozetan 125mg Tablet is given as a tablet form and can be taken with or without food. The tablets are to be taken twice daily in the morning and evening. The exact dosage and frequency of dose will be decided by the doctor on the basis of age and weight of the patient.
Are there chances of anemia with Bozetan 125mg Tablet?
Yes, there are chances that Bozetan 125mg Tablet may cause anemia. It can cause a dose-related decrease in hemoglobin in the blood which could lead to anemia. Regular hemoglobin check is advised while taking this medicine and consult your prescribing doctor for his advice. In some cases, blood transfusion is done to treat anemia.
Can I take Bozetan 125mg Tablet if I have liver problems?
It has been found that in some cases Bozetan 125mg Tablet can cause liver damage in patients who are prone to have liver disease. This medicine can also lead to increased liver enzymes. Hence, it should be used with caution in prone patients or in patients with history of liver disease. Before starting the medication inform your doctor if you have had a history of liver disease.
Is Bozetan 125mg Tablet safe in pregnancy?
No, Bozetan 125mg Tablet is not safe during pregnancy. There is evidence to show that it can cause major birth defects in the newborn baby and can harm the baby in womb. It is not advised to take Bozetan 125mg Tablet if you are planning to become pregnant. You should use reliable contraception methods while you take Bozetan 125mg Tablet. Consult your doctor before starting this medication or planning pregnancy.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 154-56.
- Bosentan. Beerse Belgium: Janssen-Cilag International NV; 2013 [revised Sep. 2018]. [Accessed 01 Apr. 2019] (online) Available from:
- Bosentan. South San Francisco, California: Actelion Pharmaceuticals US, Inc.; 2001 [revised Aug. 2009]. [Accessed 23 Jan. 2019] (online) Available from:
- Bosentan. South San Francisco, CA: Actelion Pharmaceuticals; 2001. [Accessed 01 Apr. 2019] (online) available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
- Bosentan [Prescribing Information]. Titusville, NJ: Actelion Pharmaceuticals US, Inc.; 2022. [Accessed 09 Jun, 2023] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
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