Benzz 180 Injection
Prescription Required
Product introduction
Benzz 180 Injection is used to treat cancer of the lymphatic system such as Non-Hodgkin's Lymphoma (NHL). It may also be used to treat other types of cancer as determined by your doctor. It can be used alone, or together with certain other medicines as part of combination chemotherapy.
Benzz 180 Injection is used in the treatment of many types of cancer
Benzz 180 Injection is used in the treatment of many types of cancer
Uses of Benzz Injection
Benefits of Benzz Injection
In Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Benzz 180 Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
In Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Benzz 180 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Multiple myeloma
If you have multiple myeloma, your body is destroying bone faster than it is being replaced. This makes bones weak and painful and more likely to break. Benzz 180 Injection may be prescribed along with other cancer treatments such as chemotherapy. It is an important part of your treatment and increases the survival rate of people with multiple myeloma. This medicine will kill the cancerous cells and prevent their further growth as well as spread to other parts of the body. Follow your doctor’s instructions carefully to get the most benefit. Supplements of calcium and Vitamin D3 are also effective and may be prescribed if you do not have high blood calcium levels.
Side effects of Benzz Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Benzz
- Anemia (low number of red blood cells)
- Decreased white blood cell count
- Infection
- Fatigue
- Nausea
- Fever
- Vomiting
- Low blood platelets
- Mucosal inflammation
How to use Benzz Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Benzz 180 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Benzz 180 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Benzz 180 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Benzz 180 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Benzz 180 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Benzz 180 Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Benzz 180 Injection should be used with caution in patients with liver disease. Dose adjustment of Benzz 180 Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Benzz 180 Injection is given as an injection into vein under the supervision of a doctor.
Fact Box
Chemical Class
Mechlorethamine Derivative, Alkylating Agent, {Nitrogen Mustard Drug}
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent
Patient concerns
FAQs
Is Benzz 180 Injection safe?
Benzz 180 Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
How does Benzz 180 Injection work?
Benzz 180 Injection works by destroying the DNA, thus killing the existing cancer cells and also preventing the growth and spread of new cancer cells.
Is Benzz 180 Injection a vesicant?
Benzz 180 Injection has vesicant properties and can seriously damage skin and underlying fat if leaks during administration.
Does Benzz 180 Injection cause hair loss/constipation?
Yes, hair loss and constipation are the common side effects of Benzz 180 Injection.
Does Benzz 180 Injection cross blood brain barrier?
Yes, Benzz 180 Injection crosses the blood brain barrier, and may be used to treat cancers spread to the brain.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1684.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942, 944.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 131-32.
- Bendamustine hydrochloride monohydrate. Guildford, Surrey: Zentiva; 2015 [revised 29 Aug. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
- Bendamustine hydrochloride. Lake Forest, IL: Hospira, Inc.; 2008 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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MRP
₹4776.89
Inclusive of all taxes
2.0 ml in 1 vial
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