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PhD (Pharmacology), PGDPRA
Reviewed By
MD (Pharmacology), MBBS
Last updated
26 Nov 2023 | 12:00 AM (IST)

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Astrapenem Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Astrapenem Injection is an antibiotic that is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood, and brain (eg. meningitis). It works by killing the bacteria that cause these problems. However, it will not treat a viral infection.

Astrapenem Injection is used to treat bacterial (germ) infections that affect various parts of the body normally leading to painful swelling and redness of the affected part causing varied problems

Uses of Astrapenem Injection

  • Severe bacterial infections

Benefits of Astrapenem Injection

In Severe bacterial infections

Astrapenem Injection belongs to a group of medicines called carbapenem antibiotics. It works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, blood, and heart. This medicine is usually given as an injection by a doctor or nurse.

Astrapenem Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Astrapenem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Astrapenem

  • Rash
  • Headache
  • Vomiting
  • Nausea
  • Itching
  • Diarrhea
  • Injection site inflammation
  • Anemia (low number of red blood cells)
  • Sepsis
  • Constipation
  • Apnea (absence of breathing)
  • Shock

How to use Astrapenem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Astrapenem Injection works

Astrapenem Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Safety advice

Alcohol
SAFE
Consuming alcohol with Astrapenem Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Astrapenem Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Astrapenem Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Astrapenem Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Astrapenem Injection should be used with caution in patients with kidney disease. Dose adjustment of Astrapenem Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Astrapenem Injection is safe to use in patients with liver disease. No dose adjustment of Astrapenem Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Astrapenem Injection
₹1700.0/Injection
₹2979/injection
75% costlier
Merotec 1000mg Injection
Zuventus Healthcare Ltd
₹844.15/injection
50% cheaper
Merobax 1000mg Injection
Aristo Pharmaceuticals Pvt Ltd
₹1160/injection
32% cheaper
Carbapen M 1000mg Injection
Blue Cross Laboratories Ltd
₹890/injection
48% cheaper
₹3167.86/injection
86% costlier

Quick tips

  • Astrapenem Injection is an antibiotic that's usually only given in the hospital for serious infections.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.

Fact Box

Chemical Class
Carbapenem derivative
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Cell wall active agent -Carbapenems

Patient concerns

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Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
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FAQs

Q. My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Astrapenem Injection, still, she had an episode of seizure. Why?

Any previous history with any other medication should be informed to the doctor before starting your treatment with Astrapenem Injection. Medicines like Astrapenem Injection can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.

Q. Even though Astrapenem Injection is used for skin infections, can it cause any skin-related problems?

Serious skin reactions are rare, but some have been reported with the use of Astrapenem Injection. Therefore, before starting the treatment inform your doctor if you are allergic to any medicine or antibiotic. Serious skin reactions are a type of allergic reaction. But, if not properly managed then they can endanger life. So, if you notice any rash along with fever or peeling of the skin, discontinue the medication and inform your doctor.

Q. Is Astrapenem Injection a strong antibiotic? Which infections does it treat?

Astrapenem Injection is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infections affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.

Q. Is Astrapenem Injection effective against bacteria only? Can it be used for any type of bacterial infection?

Yes, Astrapenem Injection is effective only against bacteria. It is not effective against virus or fungal infections. Astrapenem Injection is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.

Q. My cousin was receiving Astrapenem Injection for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Astrapenem Injection?

There are reports which suggest the occurrence of seizures or fits with the use of Astrapenem Injection. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.

Q. For how long will I need to take Astrapenem Injection?

The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have, and how well you respond to Astrapenem Injection. Consult your doctor if you are not sure.

Q. What if Astrapenem Injection does not suit me?

It is common to have minor side effects such as nausea, vomiting, diarrhea, and headache with the use of Astrapenem Injection. However, these symptoms generally settle down with continued medication as the body adapts to the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Astrapenem Injection are very rare. In case you develop serious side effects, seek immediate medical advice.

Q. Does it matter if I miss or stop Astrapenem Injection?

You mustn't stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Astrapenem Injection. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1500.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 866-67.
  3. Meropenem. Wilmington, DE: AstraZeneca Pharmaceuticals; 1996 [revised Nov. 2013]. [Accessed 29 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  5. Meropenem [Package Insert]. Vadodara, Gujarat: Samrudh Pharmaceuticals Pvt.Ltd.; 2021. [Accessed 11 Jul. 2023]. (online) Available from:External Link
  6. CiplaMed. Meropenem [Prescribing Information]. 03 Jun. 2021. [Accessed 11 Jul. 2023]. (online) Available from:External Link

Marketer details

Name: Astranova Biotech
Address: 4th Floor, RKL Business Center Kokane Chowk, Pimple Saudagar, Pune-411027
Country of origin: India

MRP
1700
Inclusive of all taxes
1.0 Injection in 1 vial
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