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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

Prescription Required
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Product introduction

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an injectable medicine used to lower blood glucose levels in adults with type 2 diabetes. It works by helping your body produce insulin and reducing the amount of sugar your liver makes.

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is a medicine used in the treatment of type 2 diabetes mellitus. It helps to control blood glucose levels and prevents long-term complications of diabetes. It can be used alone or as combination therapy with other diabetes medicines. Use this medicine along with a proper diet and exercise for best results. It is injected under the skin with a ready-to-use device.

Uses of Aplevant Solution for Injection

Benefits of Aplevant Solution for Injection

In Treatment of Type 2 diabetes mellitus

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an injectable medicine that helps to control high blood glucose (sugar) levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Proper control of diabetes may also lessen your risk of having a heart attack or stroke. Taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each) regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed as it is protecting your future health.

Side effects of Aplevant Solution for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aplevant

  • Nausea
  • Diarrhea
  • Vomiting
  • Abdominal pain
  • Loss of appetite

How to use Aplevant Solution for Injection

Your doctor or nurse will guide you how to use this medicine.

How Aplevant Solution for Injection works

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an anti-diabetic medication. It works by increasing the release of insulin from the pancreas, decreases hormones that raise blood sugar levels, slows down digestion, and reduces appetite.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Aplevant 1.5mg Pre-filled Pen (0.5ml Each).
Pregnancy
CONSULT YOUR DOCTOR
Aplevant 1.5mg Pre-filled Pen (0.5ml Each) may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Aplevant 1.5mg Pre-filled Pen (0.5ml Each) alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is safe to use in patients with kidney disease. No dose adjustment of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is recommended.
However, monitor renal function in patients with renal impairment reporting severe adverse gastrointestinal reactions. Use Aplevant 1.5mg Pre-filled Pen (0.5ml Each) with caution in patients with ESRD.
Liver
SAFE IF PRESCRIBED
Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • You can inject Aplevant 1.5mg Pre-filled Pen (0.5ml Each) into the same body area each week, but try not to use the exact same spot.
  • Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.
  • Do not use Aplevant 1.5mg Pre-filled Pen (0.5ml Each) if particles appear or if the solution is cloudy and/or discolored.
  • Aplevant 1.5mg Pre-filled Pen (0.5ml Each) may cause nausea, vomiting, diarrhea, or stomach pain, which may get better with time. Eat smaller meals, limit fatty food intake and inform your doctor if it does not go away.

Fact Box

Chemical Class
Glucagon-like Peptide-1 (GLP-1) Analogue
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Insulin Secretogogues: GLP-1 agonists

Patient concerns

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Diabetes mellitus type 2 ,thirst
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
Diabetes mellitus type 2 required only ayurvedic medicine
Dr. Sanjay Bhatt
Physician
Go for allopathic medicine
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FAQs

When is the best time to take Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is to be taken only once a week at any time of the day with or without food. Consult your doctor for more advice.

How is Aplevant 1.5mg Pre-filled Pen (0.5ml Each) administered?

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. It should not be injected into a muscle or vein. You can use the same area of your body each week to take the injection, but make sure that a different injection site is used within that area. Use Aplevant 1.5mg Pre-filled Pen (0.5ml Each) as advised by your doctor. You can take it with or without food. If you are on insulin as well, do not mix insulin and Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in the same syringe. It is also recommended to check your blood sugar levels regularly.

How does Aplevant 1.5mg Pre-filled Pen (0.5ml Each) work for weight loss?

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is used in type 2 diabetes mellitus. It improves blood sugar control and slows down digestion. This brings a feeling of fullness and satiety due to which the food intake by the patient decreases. As a result, the patient eats less which further helps in weight loss.

Is Aplevant 1.5mg Pre-filled Pen (0.5ml Each) an insulin?

No, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is not an insulin. It is a medicine used to lower blood sugar (glucose) levels in adults with type 2 diabetes mellitus. In type 2 diabetes insulin is deficient, and the insulin that your body produces does not work as well as it should. Aplevant 1.5mg Pre-filled Pen (0.5ml Each) acts on the pancreas to increase insulin release, suppress glucagon secretion, and decrease glucose production from the liver. It also slows down the emptying of the stomach.

Can you take Aplevant 1.5mg Pre-filled Pen (0.5ml Each) and insulin together?

Yes, your doctor may prescribe you this medicine with insulin if adequate glucose management is not obtained after using Aplevant 1.5mg Pre-filled Pen (0.5ml Each) with other antidiabetic medicines. Insulin is often used early in the treatment of individuals with complications or symptoms of extremely high blood glucose levels. If insulin is used together with Aplevant 1.5mg Pre-filled Pen (0.5ml Each), there is often greater efficacy of both medications and improved treatment outcomes. <br>

Can Aplevant 1.5mg Pre-filled Pen (0.5ml Each) be used to treat type 1 diabetes?

No, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should not be used in patients with type 1 diabetes mellitus or for the treatment of patients with diabetic ketoacidosis.

Can Aplevant 1.5mg Pre-filled Pen (0.5ml Each) cause pancreatitis?

There are reports of acute pancreatitis due to Aplevant 1.5mg Pre-filled Pen (0.5ml Each). Patients are prompted to discontinue this medicine and contact their doctor if there is persistent severe abdominal pain, sometimes radiating to the back.<br>

Is regular self-monitoring of blood sugar required while taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Regular self-monitoring of blood sugar is not needed in order to adjust the dose of Aplevant 1.5mg Pre-filled Pen (0.5ml Each). However, when initiating treatment with Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in combination with other anti-diabetic medicines, monitoring of blood sugar may become necessary to reduce the dose of the anti-diabetic medicine in order to lower the risk of hypoglycemia. <br>

What should I avoid while taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Avoid fried or fatty foods and foods high in sugar while taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each) to reduce the risk of nausea and vomiting. Eat slowly, and eat smaller meals that are light and bland.

How to store Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should be refrigerated at 2°C - 8°C, but do not freeze it. Store Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in the original packaging to protect from light. Keep the medicine out of the reach of children. Do not use the medicine if you notice that the pen is damaged or the medicine has become cloudy/discolored or has lumps in it.

Are there any potential risks of using Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Apart from the usual side effects of the medicine, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) has been found to cause Medullary Thyroid Carcinoma, a type of cancer of the thyroid gland. Its use may also increase the risk of inflammation of the pancreas commonly known as pancreatitis which is a serious and painful condition. Discontinue the medicine and contact your doctor immediately if you suspect any signs or symptoms of thyroid problems (lump in throat, hoarseness, and difficulty in speaking) or pancreatitis (stomach ache radiating to the back, upper abdominal pain, fever, nausea, and vomiting).

What is the significance of HbA1c test?

Your doctor may ask you to get your HbA1c tested every 3 months. This test is done to see how well you have managed your blood sugar for the past 2-3 months.

Can Aplevant 1.5mg Pre-filled Pen (0.5ml Each) be used with other diabetes medicine?

Yes, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) can be used alone or in combination with other diabetes medicines only if prescribed by your doctor.

Can I take a protein-rich diet along with Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

Yes, you can take a diet rich in protein along with Aplevant 1.5mg Pre-filled Pen (0.5ml Each). Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet. It is often recommended to consume about 2-3 teaspoons of proteins in the evening snacks to avert the chances of hypoglycemia.<br><br>

Can I take artificial sweeteners while taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each)?

No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.<br>

Can diabetes cause kidney failure?

Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.<br>

Can diabetes be cured?

Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Dulaglutide. Indianapolis, Indiana: Eli Lilly and Company; 2014 [revised Jan. 2017]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  2. Dulaglutide [Prescribing Information]. Indianapolis, IN: Eli Lilly and Company; 2021. [Accessed 22 Jan 2021] (online) Available from:External Link
  3. DailyMed. Dulaglutide [Prescription Drug Label]. [Accessed 28 Sept. 2021] (online) Available from:External Link
  4. Dulaglutide [Product Monograph]. Ontario, Canada: Eli Lilly Canada Inc.; 2021. [Accessed 22 Jan. 2021] (online) Available from:External Link
  5. Dulaglutide [Prescribing Information]. Indianapolis, IN: Eli Lilly and Company; 2022. [Accessed 20 June 2023]. (online) Available from:External Link

Marketer details

Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: Italy

MRP
4998
Inclusive of all taxes
2.0 Solution for Injection in 1 box
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