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05 Dec 2023 | 06:14 PM (IST)

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Ambrican 5 Tablet

Prescription Required
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Product introduction

Ambrican 5 Tablet is a prescription medicine used to treat pulmonary arterial hypertension (high pressure in the blood vessels that carry blood from the heart to the lungs). It even helps to improve your quality of life, exercising ability and delay in disease progression.

Ambrican 5 Tablet is an endothelin receptor antagonist.

Benefits of Ambrican Tablet

In Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Ambrican 5 Tablet relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.

Side effects of Ambrican Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ambrican

  • Peripheral edema
  • Nasal congestion (stuffy nose)
  • Sinus inflammation
  • Flushing (sense of warmth in the face, ears, neck and trunk)

How to use Ambrican Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ambrican 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ambrican 5 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Ambrican 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Ambrican 5 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Ambrican 5 Tablet may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
Kidney
CAUTION
Ambrican 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Ambrican 5 Tablet may be needed. Please consult your doctor.
Limited information is available on use of Ambrican 5 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Ambrican 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Ambrican 5 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Ambrican 5 Tablet
₹197.08/Tablet
₹166.3/tablet
16% cheaper
Pulmonext 5 Tablet
MSN Laboratories
₹145/tablet
26% cheaper
Volibris Tablet
Glaxo SmithKline Pharmaceuticals Ltd
₹246.95/tablet
25% costlier
Zambri 5mg Tablet
Zydus Cadila
₹145/tablet
26% cheaper
Ibitan 5mg Tablet
Indiabulls pharmaceutical ltd
₹145/tablet
26% cheaper

Quick tips

  • Your doctor has prescribed Ambrican 5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
  • It helps improve your quality of life, exercising ability, and delay disease progression.
  • Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
  • Do not drive or do anything requiring concentration until you know how Ambrican 5 Tablet affects you.
  • Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping Ambrican 5 Tablet as it is toxic to an unborn baby.
  • Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.

Fact Box

Chemical Class
Diphenylmethanes Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Endothelin receptor blocker

Patient concerns

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Having high Pulmonary Atrial Hypertension
Dr. Nabajit Talukdar
Interventional Cardiology
What medicines r u on
Hiii my wife having hurt patient ( pulmonary hypertension ) she's taking pulmonext 5mg tablet but this tablet is very costly for me of Rs. 1450/- 10tab. I want to know any another tablet available in same drugs with low price
Dr. Sfurti Mann
Diabetology
This can't be decided online Your doctor is the best judge about your patients pulmonary hypertension
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User feedback


FAQs

Can Ambrican 5 Tablet cause liver problems?

Yes, Ambrican 5 Tablet commonly causes an increase in liver enzymes. It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.

How should Ambrican 5 Tablet be taken?

Usually, the doctors advise to take one dose of Ambrican 5 Tablet. You can take it with or without food but prefer taking it at the same time each day. Swallow it whole with a glass of water. Do not crush, chew or break it into pieces.

Can I stop taking Ambrican 5 Tablet on my own?

No, you should not stop taking Ambrican 5 Tablet without consulting your doctor as this may worsen your condition. Talk to your doctor if you need to stop it.

What is the most important thing that I should know about Ambrican 5 Tablet?

Ambrican 5 Tablet may cause serious birth defects if taken during pregnancy. Therefore, every woman who is capable of becoming pregnant should get a pregnancy test done before starting Ambrican 5 Tablet. Additionally, during treatment with Ambrican 5 Tablet you should use two reliable methods of contraception to ensure that you do not get pregnant.

What are the serious side effects of Ambrican 5 Tablet?

The serious side effects of Ambrican 5 Tablet are swelling all over the body (fluid retention), decreased sperm count and low red blood cell count (anemia). Tell your doctor if you have any unusual weight gain, tiredness, or trouble breathing.

Why have I been prescribed Ambrican 5 Tablet?

Ambrican 5 Tablet is used to treat pulmonary hypertension in adults. Pulmonary hypertension is a condition wherein there is increased blood pressure in the pulmonary arteries (blood vessels that carry blood from heart to lungs). Ambrican 5 Tablet lowers the blood pressure by relaxing the pulmonary arteries, making it easier for the heart to pump blood through them.

What are the symptoms of overdose of Ambrican 5 Tablet?

Taking more than the recommended dose of Ambrican 5 Tablet may cause headache, flushing, dizziness, or nausea. It may cause low blood pressure which may further lead to lightheadedness. Contact your doctor immediately or seek emergency medical services in a nearby hospital if you take more than the recommended doses of this medicine.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Barnes PJ. Pulmonary Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1059.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 39-50.
  3. Name of medicine. Citywest Business Campus Dublin: GlaxoSmithKline (Ireland) Limited; 2008 [revised 31 Oct. 2018]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  4. Ambrisentan. Uxbridge, Middlesex: GlaxoSmithKline UK; 2008 [revised 31 Oct. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. CiplaMed. Ambrisentan [Prescribing Information]. [Last reviewed: May 2018] [Accessed 09 Jun, 2023] (online) Available from:External Link
  7. (ambrisentan) [Product Information]. [Accessed 09 Jun, 2023] (online) Available from:External Link

Marketer details

Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India

MRP
1970.85
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT

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