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MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Alpostin 500mcg Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
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Product introduction

Alpostin 500mcg Injection is used to treat patent ductus arteriosus (PDA), a heart defect that occurs in newborns. It improves blood circulation in such babies and helps treat this defect.

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Uses of Alpostin Injection

  • Treatment of Patent ductus arteriosus (PDA)

Benefits of Alpostin Injection

In Treatment of Patent ductus arteriosus (PDA)

Patent ductus arteriosus (PDA) is a persistent opening between the two major blood vessels leading from the heart. Usually this opening closes shortly after birth, but it can remain open and lead to this heart defect in babies. Alpostin 500mcg Injection improves blood flow in such babies who have PDA. It is given as an injection by a doctor or nurse in a hospital setup. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of Alpostin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alpostin

  • Apnea (absence of breathing)
  • Fever

How to use Alpostin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Alpostin Injection works

Alpostin 500mcg Injection is similar to a natural substance in the body called prostaglandin E1. It works by improving blood flow in newborn babies born with heart defects.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Alpostin 500mcg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Alpostin 500mcg Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Alpostin 500mcg Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Alpostin 500mcg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Alpostin 500mcg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Alpostin 500mcg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Alpostin 500mcg Injection
₹6372.0/Injection
Bioglandin 500mcg Injection
United Biotech Pvt Ltd
₹5850/injection
8% cheaper
₹9000/injection
41% costlier
Prostacel 500mcg Injection
Celon Laboratories Ltd
₹5650/injection
11% cheaper
₹5650/injection
11% cheaper
₹106.31/injection
98% cheaper

Fact Box

Chemical Class
Prostaglandin E1 (PGE1) Analogue
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Prostaglandin E1 (PGE1) analogue- ED

Patient concerns

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Patient having blockage from below knee to mid calf in arteries. patient had done angioplasty but it failed. He is diabetic and arteries situation is crytical so unable to go for bypass . To avoid bypass he is taking alpostin 500mcg ( 100 mcg per day)- for 5 days , piptaz and dilacin 600mg. Please suggest weather he is going is right way or not.
Dr. Mehtab Baig
Orthopaedic Physiotherapy
I am a physiotherapist , i don't give u better advice plz consult any physician or cardiology
Actually my baby is 1 month and 15 days. Two holes detect in heart of my baby from birth. Her weight is 3 kg at present and 2.5 kg birth time. So please suggest we should what to do.
Dr. Nabajit Talukdar
Interventional Cardiology
Currently nothing review echo after 3 months n see d status of pda
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Smyth EM, Grosser T, FitzGerald GA. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 952.
  2. Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 325-26.
  3. Alprostadil [EMC SmPC]. Sandwich, Kent: Pfizer Limited; 2019. [Accessed 03 Mar. 2021] (online) Available from: External Link
  4. Drugs.com. Alprostadil. [Accessed 04 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Country of origin: India

MRP
6372
Inclusive of all taxes
1.0 ml in 1 vial
SOLD OUT
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